Purpose

Developmental face blindness also referred to as developmental Prosopagnosia is estimated to affect up to 2.5 percent of the general population causing severe consequences for the quality of lives of those affected. The condition is thought to result from genetic alterations which are currently unknown. To better understand the genesis of the condition and to evaluate potential strategies for treatment the current project aims to determine the genetic underpinnings of developmental prosopagnosia through genetic testing to identify causal mutations. This study will combine genetic testing with psychophysical testing of face recognition abilities. We will recruit individuals through the following major routes. (For the first route) We have created a recruitment flyer which we will distribute in the community. This flyer contains a summary regarding the study as well as the contact information of RU"s recruitment office. Additionally to this recruitment path we will utilize a preexisting online database (https://www.faceblind.org/contactus/index.html) established by Ken Nakayama and Bradley Duchaine one of our collaborators. Potential participants will be recruited from faceblind.org where they will have expressed their willingness to participate in research beforehand. Bradley Duchaine will distribute the study flyer to the individuals who expressed interest. By applying these two strategies we hope to reach a large number of individuals from diverse communities. Through the distribution of the same flyer to all potential participants we make sure that all individuals are instructed to contact the recruitment office and undergo the same enrollment processes. The RU recruitment team will screen individuals for eligibility record demographic information and their contact information and provided the participants with their unique code for identification and provide the test link leading to the online behavioral testing. style="margin-left:29.65pt">

Condition

Eligibility

Eligible Ages
Between 18 and 99
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Ages 18 to 99 years old; male or female.
  • At least one living family member who also has Prosopagnosia
  • Normal vision in both eyes (corrected with glasses or contacts is acceptable).
  • Must have access to internet
  • Must be fluent in English

Exclusion Criteria

  • History of any brain surgery or traumatic brain injury (TBI)
  • History of psychiatric disorder currently requiring medication or treatment
  • History of stroke CVA (Cerebral Vascular Accident) or cognitive impairment especially symptoms of forgetfulness or difficulty concentrating
  • Any history of brain tumor
  • Self-reported history of colorblindness
  • History of current seizure disorder
  • Any history of encephalitis including herpetic encephalitis

Study Design

Phase
Study Type
Observational

More Details

Status
Recruiting
Sponsor
Rockefeller University

Study Contact

Recruitment Office
8007822737
rucares@rockefeller.edu

Notice

Study information shown on this site is derived from this institution's local clinical trials team. The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.